FEATURES

FAMILY

DESCRIPTION

Also known as ISCU2_ARCFU, iscU2. A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 3 ligands while IscS2 provides the other ligand. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. Forms a heterotetramer with IscS2.

EXTERNAL LINKS

uniprot
enzyme classification

iscU2

Iron-sulfur cluster assembly scaffold protein IscU 2

iscU2

Molecular Synopsis