FEATURES

FAMILY

sea anemone type 1 potassium channel toxin family

DESCRIPTION

Also known as K1HH_ANESU, K1HH. This peptide is similar to the potassium channel toxin ShK, but does not show activity on potassium channels. It appears that Lys-19, which is expected to occupy the pore of the channel, is not sufficiently accessible for binding, and therefore that this peptide must have a distinct functional role that does not involve potassium channels. It is noteworthy that this peptide is much more stable in the presence of trypsin, chymotrypsin and pepsin than the toxin ShK.

EXTERNAL LINKS

uniprot
enzyme classification

K1HH

Ask132958

K1HH

Molecular Synopsis