FEATURES

FAMILY

DESCRIPTION

Also known as DRS1_PITNO, DRS1. Antimicrobial peptide with moderate activity against both Gram-positive and Gram-negative bacteria, and important activity against Leishmania species (L.amazonensis and L.infantum) (PubMed:23774944). Acts on both Leishmania promastigote and amastigote forms (PubMed:23774944). Shows activity against E.coli (MIC=17.8 uM), S.aureus (MIC=32.3 uM) and the phytopathogenic bacterium Xanthomonas axonopodis (MIC=2 uM) (PubMed:23774944). Shows low cytotoxicity against mammalian cells in models of peritoneal macrophages (PubMed:23774944).

EXTERNAL LINKS

uniprot
enzyme classification

DRS1

Dermaseptin-N1

DRS1

Molecular Synopsis