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FEATURES

DESCRIPTION

Also known as STING_CRAGI, STING. Sensor of cytosolic DNA from bacteria and viruses that promotes autophagy (By similarity). Binds c-di-AMP, 2'3'-cGAMP, 3'3'-cGAMP and to a lesser extent c-di-GMP. Nucleotide binding has not been seen to stimulate NAD(+) hydrolase activity (PubMed:32877915). Homodimer.

Also known as STING_CRAGI, STING. Sensor of cytosolic DNA from bacteria and viruses that promotes autophagy (By similarity). Binds c-di-AMP, 2'3'-cGAMP, 3'3'-cGAMP and to a lesser extent c-di-GMP. ...

EXTERNAL LINKS

uniprot
enzyme classification

STING

Stimulator of interferon genes protein

Molecular Synopsis

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