FEATURES

DESCRIPTION

Also known as DL_DROME, Dl. Acts as a ligand for Notch (N) receptor. Essential for proper differentiation of ectoderm. Dl is required for the correct separation of neural and epidermal cell lineages. Fringe (fng) acts in the Golgi to determine the type of O-linked fucose on the EGF modules in N, altering the ability of N to bind with Delta (Dl). O-fut1 also has a role in modulating the interaction. Interacts with N via the EGF repeats and the N EGF repeats.

EXTERNAL LINKS

uniprot
enzyme classification

Dl

Neurogenic locus protein delta

Dl

Molecular Synopsis