FEATURES

FAMILY

T4likevirus baseplate wedge protein gp10 family

DESCRIPTION

Also known as BP10_BPT4, 10. Peripheral baseplate protein that is part of the tail fiber network. Connects the short tail fibers to the baseplate (PubMed:16554069). During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly. Homotrimer; disulfide-linked (PubMed:19896486, PubMed:27193680). Heteromultimer with gp7 (PubMed:19896486, PubMed:27193680); a gp10 molecule is disulfide-linked to gp7 and the other two remaining gp10 molecules form a disulfide bond (PubMed:27193680). The gp10 trimer interacts with gp11 trimer and with the short tail fiber (STF) composed of the gp12 trimer (PubMed:27193680). Part of the baseplate macromolecular complex which consists of gp5, gp5.4, gp27 (central spike complex); gp6, gp25, gp53 (inner baseplate); gp7, gp8 (intermediate baseplate); gp9, gp10, gp11, gp12 (peripheral); gp48 and gp54 (proximal region of the tail tube) (PubMed:27193680).

EXTERNAL LINKS

10

Mutations

Mutation(s) distribution

Mutations table