FEATURES

FAMILY

DESCRIPTION

Also known as ODP2_GEOSE, pdhC. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Forms a 60-polypeptide structural core with icosahedral symmetry.

EXTERNAL LINKS

uniprot
enzyme classification

pdhC

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

Mutations

Mutation(s) distribution

Mutations table

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