FEATURES

DESCRIPTION

Also known as RLBP1_HUMAN, RLBP1, CRALBP. Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. Interacts with DEGS1; the interaction increases synthesis of chromophore-precursors by DEGS1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RLBP1

Retinaldehyde-binding protein 1

RLBP1

Molecular Synopsis