FEATURES

FAMILY

DESCRIPTION

Also known as REV1_YEAST, REV1. Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis. Interacts with REV7.

EXTERNAL LINKS

uniprot
enzyme classification

REV1

DNA repair protein REV1

Mutations

Mutation(s) distribution

Mutations table

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