FEATURES

FAMILY

DESCRIPTION

Also known as ACE_HUMAN, ACE, DCP, DCP1. Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ACE

Angiotensin-converting enzyme

Mutations

Mutation(s) distribution

Mutations table

Search Mutation