FEATURES

FAMILY

DESCRIPTION

Also known as GGTA1_BOVIN, GGTA1. Synthesizes the galactose-alpha(1, 3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1, 3 linkage, on terminal lactosaminide (Gal-beta-1, 4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1, 3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3).

EXTERNAL LINKS

uniprot
enzyme classification

GGTA1

N-acetyllactosaminide alpha-1, 3-galactosyltransferase

Mutations

Mutation(s) distribution

Mutations table

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