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Also known as IGLL1_HUMAN, IGLL1, IGL1. Critical for B-cell development. Associates non-covalently with VPREB1 (PubMed:17431183). Interacts with SYNV1/HRD1 (via N-terminus); this interaction leads to increased IGLL1 ubiquitination and degradation in pre-B cells, possibly through a lysosomal, not proteasomal, pathway (By similarity).

Also known as IGLL1_HUMAN, IGLL1, IGL1. Critical for B-cell development. Associates non-covalently with VPREB1 (PubMed:17431183). Interacts with SYNV1/HRD1 (via N-terminus); this interaction leads t ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

IGLL1

Immunoglobulin lambda-like polypeptide 1

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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