FEATURES

FAMILY

DESCRIPTION

Also known as BGAL_HUMAN, GLB1, ELNR1. Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans., Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. Homodimer (PubMed:22128166). May form higher multimers (Probable).

Also known as BGAL_HUMAN, GLB1, ELNR1. Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans., Has no beta-galactosidase catalytic activity, b ...

EXTERNAL LINKS

GLB1

Beta-galactosidase

GLB1

Molecular Synopsis