FEATURES

FAMILY

DESCRIPTION

Also known as EPCAM_HUMAN, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. Monomer. Interacts with phosphorylated CLDN7.

Also known as EPCAM_HUMAN, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelia ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EPCAM

Mutations

Mutation(s) distribution

Mutations table