FEATURES

FAMILY

DESCRIPTION

Also known as HMGA1_HUMAN, HMGA1, HMGIY. HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. Interacts with HIPK2 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HMGA1

High mobility group protein HMG-I/HMG-Y

Mutations

Mutation(s) distribution

Mutations table

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