FEATURES

FAMILY

DESCRIPTION

Also known as ANPRC_HUMAN, NPR3, ANPRC, C5orf23, NPRC. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. Homodimer; disulfide-linked (PubMed:11533490). Dimers can also be formed through the C-terminal cysteine of isoform 2 (PubMed:11533490). Interacts with OSTN (By similarity).

Also known as ANPRC_HUMAN, NPR3, ANPRC, C5orf23, NPRC. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic pepti ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NPR3

Atrial natriuretic peptide receptor 3

NPR3

Molecular Synopsis