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FEATURES

FAMILY

eukaryotic AdoMetDC family

DESCRIPTION

Also known as DCAM_HUMAN, AMD1, AMD. Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels. Heterotetramer of two alpha and two beta chains.

Also known as DCAM_HUMAN, AMD1, AMD. Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine lev ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AMD1

S-adenosylmethionine decarboxylase proenzyme

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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