FEATURES

FAMILY

DESCRIPTION

Also known as PYRG1_HUMAN, CTPS1, CTPS. This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CTPS1

CTP synthase 1

CTPS1

Molecular Synopsis