FEATURES

FAMILY

mitochondrial carrier (TC 2.A.29) family

DESCRIPTION

Also known as ADT2_YEAST, PET9, AAC2. ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:24474793). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity). Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

PET9

Mutations

Mutation(s) distribution

Mutations table