FEATURES

FAMILY

carnitine/choline acetyltransferase family

DESCRIPTION

Also known as CPT2_RAT, Cpt2, Cpt-2. Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.

EXTERNAL LINKS

uniprot
enzyme classification

Cpt2

Carnitine O-palmitoyltransferase 2, mitochondrial

Cpt2

Molecular Synopsis