FEATURES

FAMILY

DESCRIPTION

Also known as THRB_MOUSE, F2, Cf2. Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). Heterodimer (named alpha-thrombin) of a light and a heavy chain; disulfide-linked. Forms a heterodimer with SERPINA5 (By similarity).

Also known as THRB_MOUSE, F2, Cf2. Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin ...

EXTERNAL LINKS

uniprot
enzyme classification

F2

Mutations

Mutation(s) distribution

Mutations table