FEATURES

FAMILY

thymidine/pyrimidine-nucleoside phosphorylase family

DESCRIPTION

Also known as TYPH_HUMAN, TYMP, ECGF1. May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro., Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TYMP

Mutations

Mutation(s) distribution

Mutations table