FEATURES

FAMILY

DESCRIPTION

Also known as ACM3_HUMAN, CHRM3. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Homodimer; the dimers can form tetramers (PubMed:23521066). Interacts with NALCN (By similarity). Interacts with TMEM147 (PubMed:21056967).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CHRM3

Muscarinic acetylcholine receptor M3

CHRM3

Molecular Synopsis