FEATURES

FAMILY

DESCRIPTION

Also known as NTR1_RAT, Ntsr1, Ntsr. G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:23051748, PubMed:24453215, PubMed:26205105). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis (By similarity). Interacts (palmitoylated form) with GNA11.

EXTERNAL LINKS

uniprot
enzyme classification

Ntsr1

Neurotensin receptor type 1

Ntsr1

Molecular Synopsis