FEATURES

FAMILY

DESCRIPTION

Also known as ASNB_ECOLI, asnB. Catalyzes the ATP-dependent conversion of aspartate into asparagine, using glutamine as a source of nitrogen. Can also use ammonia as the nitrogen source in vitro, albeit with lower efficiency. As nucleotide substrates, ATP and dATP are utilized at a similar rate in both the glutamine- and ammonia-dependent reactions, whereas GTP utilization is only 15% that of ATP, and CTP, UTP, ITP and XTP are very poor or not substrates. Also exhibits glutaminase activity. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

asnB

Asparagine synthetase B [glutamine-hydrolyzing]

Mutations

Mutation(s) distribution

Mutations table

Search Mutation