FEATURES

FAMILY

DESCRIPTION

Also known as IDS_HUMAN, IDS, SIDS. Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. Monomer (PubMed:28593992). The 58-kDa mature form is composed of two chains resulting from proteolitic processing, the 42-kDa chain and the 14-kDa chain that remain stably associated and form the 58-kDa intermediate form which is enzymatically active (PubMed:28593992).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

IDS

Iduronate 2-sulfatase

IDS

Molecular Synopsis