FEATURES

FAMILY

DESCRIPTION

Also known as HNF1A_MOUSE, Hnf1a, Hnf-1, Hnf-1a, Tcf1. Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (PubMed:19289501). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:10966642). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (PubMed:30555544). Binds DNA as a dimer (PubMed:11106484, PubMed:11439029). Heterotetramer with PCBD1; formed by a dimer of dimers (PubMed:10966642). Interacts with PCBD1 (By similarity). Interacts with BHLHE41 (PubMed:30555544).

Also known as HNF1A_MOUSE, Hnf1a, Hnf-1, Hnf-1a, Tcf1. Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver ...

EXTERNAL LINKS

uniprot
enzyme classification

Hnf1a

Hepatocyte nuclear factor 1-alpha

Hnf1a

Molecular Synopsis