FEATURES

FAMILY

DESCRIPTION

Also known as MUTL_ECOLI, mutL. This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA.

EXTERNAL LINKS

uniprot
enzyme classification

mutL

DNA mismatch repair protein MutL

Mutations

Mutation(s) distribution

Mutations table

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