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DESCRIPTION

Also known as IF4B_HUMAN, EIF4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. Self-associates and interacts with EIF3 p170 subunit.

Also known as IF4B_HUMAN, EIF4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EIF4B

Eukaryotic translation initiation factor 4B

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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