FEATURES

FAMILY

class-I pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as ALAT1_HUMAN, GPT, AAT1, GPT1. Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GPT

Alanine aminotransferase 1

GPT

Molecular Synopsis