FEATURES

FAMILY

DESCRIPTION

Also known as PRP22_YEAST, PRP22. Acts late in the splicing of pre-mRNA. Mediates the release of the spliced mRNA from spliceosomes. Belongs to the CWC complex (or CEF1-associated complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least BUD13, BUD31, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2.

EXTERNAL LINKS

uniprot
enzyme classification

PRP22

Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

Structural Ligandability

Domains Chains

0 chains assessed

PRP22

Structural Ligandability

Domains Chains

Distribution