FEATURES

FAMILY

eukaryotic RPC4/POLR3D RNA polymerase subunit family

DESCRIPTION

Also known as RPC4_YEAST, RPC53, RPC4. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for tRNA synthesis. The RPC53/RPC4-RPC37/RPC5 subcomplex is required for terminator recognition and reinitiation. Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits. Interacts with RPC37/RPC5. RPC53/RPC4, RPC37/RPC5 and RPC11/RPC10 probably form a Pol III subcomplex.

EXTERNAL LINKS

uniprot
enzyme classification

RPC53

Structural Ligandability

Domains Chains

Distribution