FEATURES

FAMILY

DESCRIPTION

Also known as BUD23_YEAST, BUD23. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of guanine 1575 (m7G1575) in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Required for efficient cleavage of the primary 35S precursor rRNA at site A2. Involved in positioning the proximal bud pole signal. Interacts with TRM112. Interacts with ECM16.

EXTERNAL LINKS

uniprot
enzyme classification

BUD23

18S rRNA (guanine(1575)-N(7))-methyltransferase

Mutations

Mutation(s) distribution

Mutations table

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