FEATURES

FAMILY

DESCRIPTION

Also known as SHDAG_HDVAM, SHDAG. Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA. RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome (By similarity). Homodimer. Homooctamer. Interacts with host RNA polymerase II complex, and with host NPM1.

EXTERNAL LINKS

uniprot
enzyme classification

SHDAG

Small delta antigen

SHDAG

Molecular Synopsis