FEATURES

FAMILY

DESCRIPTION

Also known as TKT1_ECOLI, tktA, tkt. Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Thus, catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

tktA

Transketolase 1

tktA

Molecular Synopsis