FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as GBRR2_HUMAN, GABRR2. GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission. Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GABRR2

Gamma-aminobutyric acid receptor subunit rho-2

GABRR2

Molecular Synopsis