FEATURES

FAMILY

DESCRIPTION

Also known as RXRB_HUMAN, RXRB, NR2B2. Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). Homodimer (in vitro) (PubMed:11782480). Heterodimer with other retinoic acid receptor family members. Binds DNA preferentially as a RAR/RXR heterodimer (PubMed:1310259). Interacts with NR1H3 (PubMed:12970175). Interacts with AKAP13 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RXRB

Mutations

Mutation(s) distribution

Mutations table