FEATURES

FAMILY

DESCRIPTION

Also known as KAIN_HUMAN, SERPINA4, KST, PI4. Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Monomer and some homodimers.

Also known as KAIN_HUMAN, SERPINA4, KST, PI4. Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SERPINA4

Mutations

Mutation(s) distribution

Mutations table