FEATURES

FAMILY

DESCRIPTION

Also known as EF1D_HUMAN, EEF1D, EF1D. EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome., Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). EF-1 is composed of 4 subunits: alpha, beta, delta isoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EEF1D

Elongation factor 1-delta

EEF1D

Molecular Synopsis