FEATURES

FAMILY

DESCRIPTION

Also known as GNRHR_HUMAN, GNRHR, GRHR. Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GNRHR

Gonadotropin-releasing hormone receptor

GNRHR

Molecular Synopsis