FEATURES

FAMILY

DESCRIPTION

Also known as CALCR_HUMAN, CALCR. This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin., Receptor for calcitonin but is unable to couple to G proteins and activate adenylyl cyclase (PubMed:7476993). Does not undergo receptor internalization following ligand binding (PubMed:7476993). Interacts with GPRASP2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CALCR

Calcitonin receptor

CALCR

Molecular Synopsis