FEATURES

FAMILY

sodium:solute symporter (SSF) (TC 2.A.21) family

DESCRIPTION

Also known as SC5A2_HUMAN, SLC5A2, SGLT2. Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1., Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC5A2

Sodium/glucose cotransporter 2

SLC5A2

Molecular Synopsis