FEATURES

DESCRIPTION

Also known as CBF3A_YEAST, CBF2, CBF3A, CEP2, CTF14, NDC10. Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters. Component of the CBF3 copmplex, which is formed of CBF3A/CBF2, CBF3B/CEP3, CBF3C/CTF13 and CBF3D. CBF2 strongly interacts with BIR1. Interacts with the central kinetochore protein CTF19.

Also known as CBF3A_YEAST, CBF2, CBF3A, CEP2, CTF14, NDC10. Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of ...

EXTERNAL LINKS

uniprot
enzyme classification

CBF2

Centromere DNA-binding protein complex CBF3 subunit A

CBF2

Molecular Synopsis