FEATURES

FAMILY

DESCRIPTION

Also known as VATL2_YEAST, VMA11, CLS9, TFP3. Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d and e). The proteolipid components c, c' and c'' are present as a hexameric ring that forms the proton-conducting pore.

EXTERNAL LINKS

uniprot
enzyme classification

VMA11

Mutations

Mutation(s) distribution

Mutations table