FEATURES

FAMILY

DESCRIPTION

Also known as UFM1_CAEEL, ufm-1, tag-277. Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (By similarity). The so-called ufmylation requires the ufm-1-activating E1 enzyme uba-5, the ufm-1-conjugating E2 enzyme ufc-1, and probably the ufm-1-ligase E3 enzyme ufl-1 (PubMed:23449979). Interacts with odr-8; leading to deufmylation.

EXTERNAL LINKS

uniprot
enzyme classification

ufm-1

Ubiquitin-fold modifier 1

ufm-1

Molecular Synopsis