FEATURES

FAMILY

DESCRIPTION

Also known as GLYC_HUMAN, SHMT1. Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160). Homotetramer (PubMed:24698160, PubMed:25619277, PubMed:9753690). Identified in complex with ABRAXAS2 and the other subunits of the BRISC complex, at least composed of ABRAXAS2, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1 (PubMed:24075985).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SHMT1

Serine hydroxymethyltransferase, cytosolic

Mutations

Mutation(s) distribution

Mutations table

Search Mutation