FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as GBRA3_HUMAN, GABRA3. GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1 (By similarity). Interacts with GPHN (PubMed:26613940).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GABRA3

Gamma-aminobutyric acid receptor subunit alpha-3

GABRA3

Molecular Synopsis