FEATURES

FAMILY

zinc-containing alcohol dehydrogenase family

DESCRIPTION

Also known as ADH1_ENTHI, ADH1. Alcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. Under physiological conditions, the enzyme reduces aldehydes and 2-ketones to produce secondary alcohols. Is also active with acetaldehyde and propionaldehyde. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

ADH1

NADP-dependent isopropanol dehydrogenase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation