FEATURES

FAMILY

cation transport ATPase (P-type) (TC 3.A.3) family

DESCRIPTION

Also known as ATP7B_HUMAN, ATP7B, PWD, WC1, WND. Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Monomer. Interacts with COMMD1/MURR1 (PubMed:12968035, PubMed:17919502). Interacts with DCTN4, in a copper-dependent manner (PubMed:16554302). Interacts with ATOX1 (PubMed:18558714, PubMed:17919502). Interacts (via C-terminus) with ZBTB16/PLZF (PubMed:16676348).

Also known as ATP7B_HUMAN, ATP7B, PWD, WC1, WND. Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where i ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ATP7B

Copper-transporting ATPase 2

ATP7B

Molecular Synopsis