FEATURES

FAMILY

DESCRIPTION

Also known as DEF1_YEAST, DEF1, RIP1, VID31. RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation. Interacts with the RNA polymerase II in a DNA-damaged dependent manner. Interacts with RAD26. Binds DNA.

Also known as DEF1_YEAST, DEF1, RIP1, VID31. RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, w ...

EXTERNAL LINKS

uniprot
enzyme classification

DEF1

RNA polymerase II degradation factor 1

DEF1

Structural Ligandability

Domains Chains

Distribution